Both natural DNA repaired breaks and edits leave lasting damage. This damage seems to occur with CRISPR edits as well as natural occurring breaks in DNA
"...our analysis suggests that the corresponding resource-limited production peak will occur soon, between perhaps 2022 to 2025. If then we add tar sands and Orinoco oil, the expected resource-limited total peak occurs around 2030, although there is a major question over whether significantly increased production rates of the latter two classes of oil is possible. Finally, the resource-limited production peak of global ‘all-liquids’ is expected about 2040 or a bit after if the latter liquids are also produced at the maximal rate"